​BIFOCAlps main objective is to boost collaboration and synergies among main actors of the Alpine Space innovation system for a sustainable, smart and competitive development of the manufacturing value chain towards the Factory of the Future (FoF). ​Since its implementation, the BIFOCAlps project has achieved several key outcomes. It successfully increased collaboration and synergies among the main actors in the Alpine region’s innovation system, driving innovation for sustainable and competitive development in the manufacturing value chain towards the Factory of the Future. The project developed a comprehensive map of the manufacturing sector at a transnational level, highlighting existing and potential best practices, technologies, and competencies throughout the value chain. Additionally, BIFOCAlps established guidelines for strategic actions aimed at influencing policy agendas, based on an impact indicator system, to monitor and allow the evaluation of performance in line with harmonisation of Smart Specialisation Strategies (S3). ​This practice is unique and innovative due to its “bifocal” view, which simultaneously considers both the upstream and downstream segments of the value chain. By integrating the transversal competencies of business, research, and policy actors at a transnational level, the project facilitates the gathering of best-case scenarios across the Alpine Space (AS). This enables the integration and implementation of these scenarios into a validated methodology that builds on prior results. Moreover, the practice is designed to be transferable at cross-national and cross-sectoral level aiming to connect the value chain and boost competitiveness of the whole AS in the long term.